New test for sensitivity evaluation of Trichomonas vaginalis to nitroimidazoles and nitrofurans in vitro

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New test for sensitivity evaluation of Trichomonas vaginalis to nitroimidazoles and nitrofurans in vitro

Trichomonas vaginalis (Tv) is a causative agent of worldwide spread sexually transmitted disease, particularly affecting underdeveloped all segments of the population. Metronidazole is by far the most prescribed drug for the treatment of trichomoniasis. However, the appearance of drug resistant has led to the appearance of new drug alternatives. That is why the development of reliable and stand...

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Strain of Trichomonas vaginalis resistant to metronidazole and other 5-nitroimidazoles.

A strain of Trichomonas vaginalis (IR-78), recently isolated from a patient afflicted with recurrent symptomatic trichomoniasis, showed resistance to metronidazole, tinidazole, and nimorazole in vitro as well as in vivo. In a serial dilution test using cysteine monohydrochloride-peptone-liver infusion-maltose medium, T. vaginalis IR-78 was only resistant under aerobic conditions. Under anaerobi...

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Drug Susceptibility of Trichomonas vaginalis to Metronidazole in Bushehr City (In Vitro)

Background: Trichomoniasis is the most common non-viral sexually transmitted disease caused by the protozoan parasite Trichomonas vaginalis. Metronidazole (MTZ), a 5-nitroimidazole derivative, is the main antitrichomonal agent of choice for the treatment of trichomoniasis. Since 1962, some cases of treatment failure with metronidazole have been reported, and the increased resistance of the para...

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Comparison of direct microscopic examination and culture methods sensitivity for diagnosis of Trichomonas vaginalis in Tabriz health care centers visitors

Background: Trichomonas vaginalis is a common pathogen with worldwide distribution. It is estimated that worldwide 180 million people are infected annually. Trichomoniasis is associated with vaginitis, cervicitis, low birth weight, and preterm delivery in pregnant women in addition, it is a cofactor in HIV transmission. Diagnosis of disease is traditionally depends on the microscopic observatio...

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ژورنال

عنوان ژورنال: BMC Proceedings

سال: 2011

ISSN: 1753-6561

DOI: 10.1186/1753-6561-5-s1-p97